Is chemo necessary for HER2-positive? Because HER2-positive cancer is considered more aggressive than HER2-negative breast cancer, it is usually treated with chemotherapy after surgery to reduce recurrence risk.
What is the survival rate of HER2-positive breast cancer? The survival rate at four years among women with HR+/HER2− is estimated to be 92.5%, followed by HR+/HER2+ at 90.3%, HR−/HER2+ at 82.7%, and HR−/HER2− at 77.0% . The HER2 (human epidermal growth factor receptor 2) oncogene is positive in about 20% of primary invasive breast cancers .
Is it better to have HER2-positive breast cancer? Breast cancer identified as HER2-positive tends to grow faster, spread (metastatic breast cancer) and come back (recur). While HER2-positive cancer may be aggressive, it also responds better to breast cancer treatment that targets HER2 protein.
What is the new drug for HER2-positive breast cancer? Trastuzumab Deruxtecan Improves Progression-Free Survival, Shrinks More Tumors. The DESTINY-Breast03 trial enrolled 524 people with HER2-positive breast cancer that could not be removed by surgery or had metastasized to other parts of the body, including the brain.