What type of breast cancer does BRCA cause? That’s why genetic counseling is very important. Q: What types of cancer do the BRCA genes cause? Mutations in the BRCA genes cause Hereditary Breast and Ovarian Cancer Syndrome (HBOC). The lifetime risk for breast cancer is estimated to be 55 to 85 percent, and the lifetime risk for ovarian cancer is 27 to 44 percent.
How likely are you to get breast cancer if you have the BRCA gene? “Having a BRCA mutation means you have a likelihood of 45% to 85% for developing breast cancer in your lifetime, along with a 10% to 46% chance of ovarian cancer,” Euhus says. “That’s considerably more than the probability of breast cancer among the general population, which is about 12%, or about one in eight.
Does the BRCA gene mean you will get cancer? BRCA1 and BRCA2 are examples of genes that raise your cancer risk if they become altered. Having a variant BRCA gene greatly increases a woman’s chance of developing breast cancer and ovarian cancer. They also increase a man’s chance of developing male breast cancer and prostate cancer.
Is BRCA breast cancer more aggressive? Mutations in the BRCA 1 or 2 genes significantly increase an individual’s risk of developing breast cancer, as well as several other cancer types. Breast cancers related to a BRCA mutation are also more likely to be triple-negative breast cancer (TNBC), which can be more aggressive and difficult to treat.