What is the survival rate of multicentric breast cancer? The disease-free survival rates in the multifocal/multicentric group at 5 and 10 years were 75% and 71%, respectively, versus 87% and 78% at 10 years (p = 0.01). On multivariate analysis, multifocal/multicentric disease was no longer associated with worse disease-free survival.
How common is multicentric breast cancer? Multifocal and multicentric breast cancer (MMBC) is common, with a reported incidence of 9–75%. Incidence varies according to the extent of breast tissue sampling, but this wide range of reported incidence also reflects the lack of a standard definition of MMBC.
What is treatment for multicentric breast cancer? “It would be nice to see trials of breast-conserving therapy in a well-defined population of patients with multicentric breast cancer,” Dr. Morrow said. However, she emphasized, “mastectomy remains the standard therapy for multicentric breast cancer detected clinically or by mammography.”
Is multicentric breast cancer rare? Abstract. Multiple synchronous (multifocal or multicentric) ipsilateral breast cancers with heterogeneous histopathology are a rare clinical occurrence, however, their incidence is increasing due to the use of MRI for breast cancer screening and staging.